to disturb greatly; to perturb; to throw into confusion ...1657 obs.
from Latin conturbat-,
ppl. stem of conturbare to disturb greatly, to throw into confusion
from con- + turbare to disturb
FIRST DOCUMENTED USE
1657 - see Example below
"...for the inveterate is imbecil, and conturbates the bowels."
From: Renodæus' Medicinal Dispensatory,
Richard Tomlinson, translated 1657
• A New English Dictionary on Historical Principles,
James Murray, 1887-1933